Bones is a bare-bones responsive grid similar to bootstrap and very similar (and loosely based on) skeleton. It is written in LESS and gives the developer 100% fine grained control over everything. If your're a type-A control freak, you'll love Bones. What are the benefits of Bones other than sharing names with an awesome show?
Implementing bones is fairly straightforward, but because it is written in LESS it requires some additional tools in order compile the LESS file into a CSS. Find more information on LESS on their website. If you are developing in windows, I would like to suggest WinLESS to pre-compile you LESS files into CSS prior publish. I do not recommend compiling the LESS file on the client via the JavaScript plugin.
You can find the full documentation on my webpage as well as links to download the framework.